✔ Among the infectious diseases, cardiovascular
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Among the infectious diseases, cardiovascular diseases: the context and clinical relevance of
Infectious diseases can not only affect directly the respiratory system, the digestive system or the skin, but also, indirectly, the cardiovascular system damage. The connection between infections and cardiovascular diseases (HKK) is classified in the modern cardiology is increasingly important.
One of the most well-known mechanisms, the myokarditise — an inflammation of the heart muscle, which is often triggered by viruses. Among the most common pathogens:
Enteroviruses (e.g., Coxsackie virus),
Adenoviruses,
Parvovirus B19,
Herpes Simplex Virus Types.
The viruses penetrate into the Cardiomyocytes, trigger an immune-mediated inflammatory response and can lead to disruption of the Contraction and the conduction function of the heart. Clinically, this can range from asymptomatic gradients to heart failure, arrhythmias or even sudden cardiac death.
Another important example is rheumatic heart disease, which occurs as a result of a streptococcal infection of the upper respiratory tract (e.g., Streptococcus pyogenes) is. Here reaction develops due to an autoimmune inflammation of the heart valves, in particular, the Mitalklappe. In the long term, this can lead to valve defects, and chronic heart failure.
Systemic infections such as Sepsis or bacterial endocarditis can be a burden on the cardiovascular system. In the case of endocarditis bacteria (often streptococci or staphylococci) colonize the heart valves surfaces and Vegeta form functions, which can lead to valve damage, embolism, and congestive heart failure.
In addition, epidemiological studies show that chronic infections (for example, periodontal disease, chronic lung infections) are associated with an increased risk for atherosclerosis and coronary heart disease. Probably a long-lasting systemic inflammation contributes to the activation to the Progression of vascular calcification.
For the diagnosis of infection-related cardiovascular diseases include:
Laboratory parameters (CRP, Troponin, BNP),
serological tests for the identification of Pathogens,
Echocardiography,
Magnetic resonance imaging (CMR) for the detection of myocardial edema and fibrosis,
if necessary, endomyocardial biopsy.
The therapy depends on the pathogen and the Severity of the disease. It includes:
anti-viral or anti-bacterial drugs,
anti-inflammatory therapy,
symptomatic treatment of heart failure and arrhythmias,
in the case of valve damage, if applicable, operating valves repair or replacement.
Conclusion: infectious diseases are a significant cause of cardiovascular diseases. Early detection and adequate treatment of the infection, as well as a close interdisciplinary collaboration between Infectious disease specialists, and cardiologists are crucial for the prognosis of the patients.
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